A Critical Role of Mitochondrial Phosphatase Ptpmt1 in Embryogenesis Reveals a Mitochondrial Metabolic Stress-Induced Differentiation Checkpoint in Embryonic Stem Cells

Mitochondria are highly dynamic organelles that play multiple roles in cells. How mitochondria cooperatively modulate embryonic stem (ES) cell function during development is not fully understood. Global disruption of Ptpmt1, a mitochondrial Pten-like phosphatidylinositol phosphate (PIP) phosphatase,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shen, Jinhua, Liu, Xia, Yu, Wen-Mei, Liu, Jie, Groot Nibbelink, Milou, Guo, Caiying, Finkel, Toren, Qu, Cheng-Kui
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2011
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233018/
https://ncbi.nlm.nih.gov/pubmed/21986498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05629-11
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