Differential Association of Plasmodium falciparum Na(+)/H(+) Exchanger Polymorphism and Quinine Responses in Field- and Culture-Adapted Isolates of Plasmodium falciparum

Plasmodium falciparum isolates with decreased susceptibility to quinine are increasingly being found in malaria patients. Mechanisms involved in this resistance are not yet understood. Several studies claim that alongside mutations in the Pfcrt and Pfmdr1 genes, the Pfnhe-1 Na(+)/H(+) exchanger poly...

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Detalhes bibliográficos
Main Authors: Pelleau, Stéphane, Bertaux, Lionel, Briolant, Sébastien, Ferdig, Michael T., Sinou, Véronique, Pradines, Bruno, Parzy, Daniel, Jambou, Ronan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232819/
https://ncbi.nlm.nih.gov/pubmed/21947391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00477-11
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