In vitro susceptibility to quinine and microsatellite variations of the Plasmodium falciparum Na(+)/H(+ )exchanger (Pfnhe-1) gene: the absence of association in clinical isolates from the Republic of Congo

BACKGROUND: Quinine is still recommended as an effective therapy for severe cases of Plasmodium falciparum malaria, but the parasite has developed resistance to the drug in some cases. Investigations into the genetic basis for quinine resistance (QNR) suggest that QNR is complex and involves several...

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Détails bibliographiques
Auteurs principaux: Briolant, Sébastien, Pelleau, Stéphane, Bogreau, Hervé, Hovette, Philippe, Zettor, Agnès, Castello, Jacky, Baret, Eric, Amalvict, Rémy, Rogier, Christophe, Pradines, Bruno
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055222/
https://ncbi.nlm.nih.gov/pubmed/21314947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-37
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