Plasmodium falciparum Na(+)/H(+) Exchanger 1 Transporter Is Involved in Reduced Susceptibility to Quinine

Polymorphisms in the Plasmodium falciparum crt (Pfcrt), Pfmdr1, and Pfmrp genes were not significantly associated with quinine (QN) 50% inhibitory concentrations (IC(50)s) in 23 strains of Plasmodium falciparum. An increased number of DNNND repeats in Pfnhe-1 microsatellite ms4760 was associated wit...

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Detalhes bibliográficos
Main Authors: Henry, Maud, Briolant, Sébastien, Zettor, Agnès, Pelleau, Stéphane, Baragatti, Meili, Baret, Eric, Mosnier, Joel, Amalvict, Rémy, Fusai, Thierry, Rogier, Christophe, Pradines, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681529/
https://ncbi.nlm.nih.gov/pubmed/19273668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01243-08
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