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Functional Promoter Haplotypes of Interleukin-18 Condition Susceptibility to Severe Malarial Anemia and Childhood Mortality

Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children residing in regions where Plasmodium falciparum transmission is holoendemic. Although largely unexplored in children with SMA, interleukin-18 (IL-18) is important for regulating innate and acquired immunity in inf...

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Bibliografiske detaljer
Main Authors: Anyona, Samuel B., Kempaiah, Prakasha, Raballah, Evans, Ouma, Collins, Were, Tom, Davenport, Gregory C., Konah, Stephen N., Vulule, John M., Hittner, James B., Gichuki, Charity W., Ong'echa, John M., Perkins, Douglas J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232671/
https://ncbi.nlm.nih.gov/pubmed/21969001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05601-11
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