Transgenic Analysis of the Role of FKBP12.6 in Cardiac Function and Intracellular Calcium Release

FK506 binding protein12.6 (FKBP12.6) binds to the Ca(2+) release channel ryanodine receptor (RyR2) in cardiomyocytes and stabilizes RyR2 to prevent premature sarcoplasmic reticulum Ca(2+) release. Previously, two different mouse strains deficient in FKBP12.6 were reported to have different abnormal...

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Detalhes bibliográficos
Main Authors: Liu, Ying, Chen, Hanying, Ji, Guangju, Li, Baiyan, Mohler, Peter J., Zhu, Zhiming, Yong, Weidong, Chen, Zhuang, Xu, Xuehong, Xin, Hongbo, Shou, Weinian
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232634/
https://ncbi.nlm.nih.gov/pubmed/22087651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2011.0411
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