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Mutations in the E1a gene of adenovirus type 5 alter the tumorigenic properties of transformed cloned rat embryo fibroblast cells.

The adenovirus type 5 mutants H5hr1 and H5dl101 contain modifications in the E1a gene affecting the 13S mRNA-encoded 289-amino acid polypeptide and exhibit a cold-sensitive transformation phenotype upon infection of cloned rat embryo fibroblast (CREF) cells. Transformed cell lines expressing solely...

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Main Authors: Babiss, L E, Liaw, W S, Zimmer, S G, Godman, G C, Ginsberg, H S, Fisher, P B
格式: Artigo
語言:Inglês
出版: 1986
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC323252/
https://ncbi.nlm.nih.gov/pubmed/2938185
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