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Deletion and insertion mutations in early region 1a of type 5 adenovirus that produce cold-sensitive or defective phenotypes for transformation.

On the basis of earlier findings showing that H5hr1 (hr1) is cold sensitive for transformation, a series of mutants were constructed so that they contained deletions or insertions in different sites of early region 1a (E1a) to ascertain: (i) whether the cold-sensitive phenotype of hr1 was the result...

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Autors principals: Babiss, L E, Fisher, P B, Ginsberg, H S
Format: Artigo
Idioma:Inglês
Publicat: 1984
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC255531/
https://ncbi.nlm.nih.gov/pubmed/6699937
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