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Mutations in the E1a gene of adenovirus type 5 alter the tumorigenic properties of transformed cloned rat embryo fibroblast cells.

The adenovirus type 5 mutants H5hr1 and H5dl101 contain modifications in the E1a gene affecting the 13S mRNA-encoded 289-amino acid polypeptide and exhibit a cold-sensitive transformation phenotype upon infection of cloned rat embryo fibroblast (CREF) cells. Transformed cell lines expressing solely...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Babiss, L E, Liaw, W S, Zimmer, S G, Godman, G C, Ginsberg, H S, Fisher, P B
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323252/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2938185/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.7.2167
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