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Rare occurrence of DNMT3A mutations in myelodysplastic syndromes

Gene mutations and epigenetic changes have been shown to play significant roles in the pathogenesis of myelodysplastic syndromes. Recently, mutations in DNMT3A were identified in 22.1% of patients with acute myeloid leukemia. In this study, we analyzed the frequency and clinical impact of DNMT3A mut...

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Hlavní autoři: Thol, Felicitas, Winschel, Claudia, Lüdeking, Andrea, Yun, Haiyang, Friesen, Inna, Damm, Frederik, Wagner, Katharina, Krauter, Jürgen, Heuser, Michael, Ganser, Arnold
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232272/
https://ncbi.nlm.nih.gov/pubmed/21880636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.045559
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