IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis

BACKGROUND: Myelodysplastic syndromes are a heterogeneous group of hematopoietic stem cell disorders with a high propensity to transform into acute myeloid leukemia. Heterozygous missense mutations in IDH1 at position R132 and in IDH2 at positions R140 and R172 have recently been reported in acute m...

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Bibliografski detalji
Glavni autori: Thol, Felicitas, Weissinger, Eva M., Krauter, Jürgen, Wagner, Katharina, Damm, Frederik, Wichmann, Martin, Göhring, Gudrun, Schumann, Christiane, Bug, Gesine, Ottmann, Oliver, Hofmann, Wolf-Karsten, Schlegelberger, Brigitte, Ganser, Arnold, Heuser, Michael
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2010
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948091/
https://ncbi.nlm.nih.gov/pubmed/20494930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.025494
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