Rare occurrence of DNMT3A mutations in myelodysplastic syndromes

Gene mutations and epigenetic changes have been shown to play significant roles in the pathogenesis of myelodysplastic syndromes. Recently, mutations in DNMT3A were identified in 22.1% of patients with acute myeloid leukemia. In this study, we analyzed the frequency and clinical impact of DNMT3A mut...

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Autors principals: Thol, Felicitas, Winschel, Claudia, Lüdeking, Andrea, Yun, Haiyang, Friesen, Inna, Damm, Frederik, Wagner, Katharina, Krauter, Jürgen, Heuser, Michael, Ganser, Arnold
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2011
Matèries:
Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232272/
https://ncbi.nlm.nih.gov/pubmed/21880636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.045559
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