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Tyrosine Phosphorylation of Rac1: A Role in Regulation of Cell Spreading

Rac1 influences a multiplicity of vital cellular- and tissue-level control functions, making it an important candidate for targeted therapeutics. The activity of the Rho family member Cdc42 has been shown to be modulated by tyrosine phosphorylation at position 64. We therefore investigated consequen...

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Autores principales: Chang, Fumin, Lemmon, Christopher, Lietha, Daniel, Eck, Michael, Romer, Lewis
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232246/
https://ncbi.nlm.nih.gov/pubmed/22163037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028587
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