PECAM1 regulates flow-mediated Gab1 tyrosine phosphorylation and signaling

Endothelial dysfunction, characterized by impaired activation of endothelial nitric oxide (NO) synthase (eNOS) and ensued decrease of NO production, is a common mechanism of various cardiovascular pathologies, including hypertension and atherosclerosis. Laminar blood flow-mediated specific signaling...

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Bibliographic Details
Published in:Cell Signal
Main Authors: Xu, Suowen, Ha, Chang Hoon, Wang, Weiye, Xu, Xiangbin, Yin, Meimei, Jin, Felix Q., Mastrangelo, Michael, Koroleva, Marina, Fujiwara, Keigi, Jin, Zheng Gen
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724494/
https://ncbi.nlm.nih.gov/pubmed/26706435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.12.007
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