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Crystallization and preliminary X-ray diffraction analysis of mouse prostaglandin F(2α) synthase, AKR1B3
Aldo-keto reductase 1B3 (AKR1B3) catalyzes the NADPH-dependent reduction of prostaglandin H(2) (PGH(2)), which is a common intermediate of various prostanoids, to form PGF(2α). AKR1B3 also reduces PGH(2) to PGD(2) in the absence of NADPH. AKR1B3 produced in Escherichia coli was crystallized in compl...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
International Union of Crystallography
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3232157/ https://ncbi.nlm.nih.gov/pubmed/22139184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111036165 |
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