Crystallization and preliminary X-ray diffraction analysis of mouse prostaglandin F(2α) synthase, AKR1B3

Aldo-keto reductase 1B3 (AKR1B3) catalyzes the NADPH-dependent reduction of prostaglandin H(2) (PGH(2)), which is a common intermediate of various prostanoids, to form PGF(2α). AKR1B3 also reduces PGH(2) to PGD(2) in the absence of NADPH. AKR1B3 produced in Escherichia coli was crystallized in compl...

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Detalhes bibliográficos
Main Authors: Takashima, Yasuhide, Hatanaka, Seika, Mizohata, Eiichi, Nagata, Nanae, Fukunishi, Yoshifumi, Matsumura, Hiroyoshi, Urade, Yoshihiro, Inoue, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Crystallization Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232157/
https://ncbi.nlm.nih.gov/pubmed/22139184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111036165
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