miR-200 Inhibits Lung Adenocarcinoma Cell Invasion and Metastasis by Targeting Flt1/VEGFR1

The microRNA-200 (miR-200) family is part of a gene expression signature that predicts poor prognosis in lung cancer patients. In a mouse model of K-ras/p53-mutant lung adenocarcinoma, miR-200 levels are suppressed in metastasis-prone tumor cells, and forced miR-200 expression inhibits tumor growth...

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Detalhes bibliográficos
Main Authors: Roybal, Jonathon D., Zang, Yi, Ahn, Young-Ho, Yang, Yanan, Gibbons, Don L., Baird, Brandi N., Alvarez, Cristina, Thilaganathan, Nishan, Liu, Diane D., Saintigny, Pierre, Heymach, John V., Creighton, Chad J., Kurie, Jonathan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232024/
https://ncbi.nlm.nih.gov/pubmed/21115742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0497
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