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Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

Metastatic disease is a primary cause of cancer-related death, and factors governing tumor cell metastasis have not been fully elucidated. Here, we address this question by using tumor cell lines derived from mice that develop metastatic lung adenocarcinoma owing to expression of mutant K-ras and p5...

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Hlavní autoři: Gibbons, Don L., Lin, Wei, Creighton, Chad J., Rizvi, Zain H., Gregory, Philip A., Goodall, Gregory J., Thilaganathan, Nishan, Du, Liqin, Zhang, Yiqun, Pertsemlidis, Alexander, Kurie, Jonathan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751985/
https://ncbi.nlm.nih.gov/pubmed/19759262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1820209
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