The microRNA-200/Zeb1 axis regulates ECM-dependent β1-integrin/FAK signaling, cancer cell invasion and metastasis through CRKL

Tumor cell metastasis is a complex process that has been mechanistically linked to the epithelial-mesenchymal transition (EMT). The double-negative feedback loop between the microRNA-200 family and the Zeb1 transcriptional repressor is a master EMT regulator, but there is incomplete understanding of...

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Publicado no:Sci Rep
Main Authors: Ungewiss, Christin, Rizvi, Zain H., Roybal, Jonathon D., Peng, David H., Gold, Kathryn A., Shin, Dong-Hoon, Creighton, Chad J., Gibbons, Don L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700473/
https://ncbi.nlm.nih.gov/pubmed/26728244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18652
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