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Comparative Performance of Cell Life Span and Cell Transit Models for Describing Erythropoietic Drug Effects

Prolonged time delay in response to drug action is a common feature of hematological responses to pharmacotherapy such as erythropoiesis. The objective of this study was to compare the performance of two competing modeling approaches for delayed drug effects, mechanistic cell life span models, and s...

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Bibliografski detalji
Glavni autori: Budha, Nageshwar R., Kovar, Andreas, Meibohm, Bernd
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3231865/
https://ncbi.nlm.nih.gov/pubmed/22005901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-011-9302-9
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