Requirement for MLL3 in p53 Regulation of Hepatic Expression of Small Heterodimer Partner and Bile Acid Homeostasis

The histone H3-lysine-4 methyltransferase mixed-lineage leukemia 3 (MLL3) belongs to a large complex that functions as a coactivator of multiple transcription factors, including the bile acid (BA)-activated nuclear receptor, farnesoid X receptor (FXR), a critical player in BA homeostasis. BA-activat...

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Main Authors: Kim, Dae-Hwan, Kim, Juhee, Lee, Jae W.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2011
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3231838/
https://ncbi.nlm.nih.gov/pubmed/22034226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1198
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