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Frequent lambda light chain gene rearrangement and expression in a Ly-1 B lymphoma with a productive kappa chain allele.

We describe here a murine Ly-1-bearing pre-B-cell tumor that, when induced for kappa light chain expression with bacterial lipopolysaccharide, also gives rise spontaneously to a few percent of cells expressing surface lambda light chains. These lambda-positive cells have undergone DNA rearrangements...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Hardy, R R, Dangl, J L, Hayakawa, K, Jager, G, Herzenberg, L A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323091/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3081897/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.5.1438
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