Frequent lambda light chain gene rearrangement and expression in a Ly-1 B lymphoma with a productive kappa chain allele.

We describe here a murine Ly-1-bearing pre-B-cell tumor that, when induced for kappa light chain expression with bacterial lipopolysaccharide, also gives rise spontaneously to a few percent of cells expressing surface lambda light chains. These lambda-positive cells have undergone DNA rearrangements...

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Detalles Bibliográficos
Main Authors: Hardy, R R, Dangl, J L, Hayakawa, K, Jager, G, Herzenberg, L A
Formato: Artigo
Idioma:Inglês
Publicado: 1986
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC323091/
https://ncbi.nlm.nih.gov/pubmed/3081897
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