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Frequent lambda light chain gene rearrangement and expression in a Ly-1 B lymphoma with a productive kappa chain allele.

We describe here a murine Ly-1-bearing pre-B-cell tumor that, when induced for kappa light chain expression with bacterial lipopolysaccharide, also gives rise spontaneously to a few percent of cells expressing surface lambda light chains. These lambda-positive cells have undergone DNA rearrangements...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Hardy, R R, Dangl, J L, Hayakawa, K, Jager, G, Herzenberg, L A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1986
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323091/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3081897/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.5.1438
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