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The t(8;14) chromosome translocation of the Burkitt lymphoma cell line Daudi occurred during immunoglobulin gene rearrangement and involved the heavy chain diversity region.

Recent molecular analyses of Burkitt lymphomas carrying the t(8;14) chromosome translocation have indicated that a dichotomy exists regarding the molecular mechanisms by which the translocations occur. Most sporadic Burkitt tumors carry translocations that apparently arise due to mistakes in the imm...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Haluska, F G, Tsujimoto, Y, Croce, C M
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1987
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299179/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3116544/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.19.6835
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