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Functional Implications of Structural Predictions for Alternative Splice Proteins Expressed in Her2/neu–Induced Breast Cancers
Alternative splicing allows a single gene to generate multiple mRNA transcripts, which can be translated into functionally diverse proteins. However, experimentally-determined structures of protein splice isoforms are rare, and homology modeling methods are poor at predicting atomic-level structural...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230717/ https://ncbi.nlm.nih.gov/pubmed/22003824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr200772w |
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