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A New Class of Protein Cancer Biomarker Candidates: Differentially-Expressed Splice Variants of ERBB2 (HER2/neu) and ERBB1 (EGFR) in Breast Cancer Cell Lines

Combined RNA-Seq and proteomics analyses reveal striking differential expression of splice isoforms of key proteins in important cancer pathways and networks. Even between primary tumor cell lines from histologically-similar inflammatory breast cancers, we find striking differences in hormone recept...

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Detalhes bibliográficos
Main Authors: Omenn, Gilbert S., Guan, Yuanfang, Menon, Rajasree
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123867/
https://ncbi.nlm.nih.gov/pubmed/24802673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2014.04.012
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