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Alternative Splice Variants, a New Class of Protein Cancer Biomarker Candidates: Findings in Pancreatic Cancer and Breast Cancer with Systems Biology Implications

Alternative splicing plays an important role in protein diversity without increasing genome size. Earlier thought to be uncommon, splicing appears to affect the majority of genes. Alternative splice variants have been detected at the mRNA level in many diseases. We have designed and demonstrated a d...

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Detalhes bibliográficos
Main Authors: Omenn, Gilbert S., Yocum, Anastasia K., Menon, Rajasree
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833236/
https://ncbi.nlm.nih.gov/pubmed/20534909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/DMA-2010-0702
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