In silico discovery of novel Retinoic Acid Receptor agonist structures

BACKGROUND: Several Retinoic Acid Receptors (RAR) agonists have therapeutic activity against a variety of cancer types; however, unacceptable toxicity profiles have hindered the development of drugs. RAR agonists presenting novel structural and chemical features could therefore open new avenues for...

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Εκδόθηκε σε:	BMC Struct Biol
Κύριοι συγγραφείς:	Schapira, Matthieu, Raaka, Bruce M, Samuels, Herbert H, Abagyan, Ruben
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2001
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC32304/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11405897/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1472-6807-1-1
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