Smac mimetic reverses resistance to TRAIL and chemotherapy in human urothelial cancer cells

PURPOSE: Inhibitors of apoptosis proteins (IAP s) have been shown to contribute to resistance of neoplastic cells to chemotherapy and to biologic antineoplastic agents. Consequently, new agents are being developed targeting this family of proteins. In a panel of bladder cancer cell lines, we evaluat...

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Detalles Bibliográficos
Autores principales: Metwalli, Adam R, Khanbolooki, Sanaz, Jinesh, Goodwin, Sundi, Debasish, Shah, Jay B, Shrader, Marissa, Choi, Woonyoung, Lashinger, Laura M, Chunduru, Srinivas, McConkey, David J, McKinlay, Mark, Kamat, Ashish M
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2010
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230293/
https://ncbi.nlm.nih.gov/pubmed/20814238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.9.13237
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