Smac mimetic reverses resistance to TRAIL and chemotherapy in human urothelial cancer cells

PURPOSE: Inhibitors of apoptosis proteins (IAP s) have been shown to contribute to resistance of neoplastic cells to chemotherapy and to biologic antineoplastic agents. Consequently, new agents are being developed targeting this family of proteins. In a panel of bladder cancer cell lines, we evaluat...

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Detalhes bibliográficos
Main Authors: Metwalli, Adam R, Khanbolooki, Sanaz, Jinesh, Goodwin, Sundi, Debasish, Shah, Jay B, Shrader, Marissa, Choi, Woonyoung, Lashinger, Laura M, Chunduru, Srinivas, McConkey, David J, McKinlay, Mark, Kamat, Ashish M
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230293/
https://ncbi.nlm.nih.gov/pubmed/20814238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.9.13237
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