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Smac mimetic enables the anticancer action of BCG-stimulated neutrophils through TNF-α but not through TRAIL and FasL

BCG, the current gold standard immunotherapy for bladder cancer, exerts its activity via recruitment of neutrophils to the tumor microenvironment. Many patients do not respond to BCG therapy, indicating the need to understand the mechanism of action of BCG-stimulated neutrophils and to identify ways...

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Detalhes bibliográficos
Main Authors: Jinesh G., Goodwin, Chunduru, Srinivas, Kamat, Ashish M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382315/
https://ncbi.nlm.nih.gov/pubmed/22517918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1211623
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