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Seebach’s Conjunctive Reagent Enables Double Cyclizations

[Image: see text] When ketones flanked on both sides by nucleophilic atoms react with Seebach’s nitropropenyl pivaloate reagent, direct couplings take place to give two new ring systems and three bonds. cis-Ring fusions are observed in unions leading to 5,5-, 5,6-, and 6,6-bicycles. Densely function...

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Détails bibliographiques
Auteurs principaux: Chandler, Brent D., Roland, Jason T., Li, Yukai, Sorensen, Erik J.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230265/
https://ncbi.nlm.nih.gov/pubmed/20481611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100845z
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