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Stereoselectivity of Intramolecular S(N)′ Cyclizations of Alkyllithium Reagents on Methoxy Alkenes

The cyclization of alkyllithium reagents onto methoxy alkenes has been investigated. The alkyllithium reagent was generated by reductive lithiation of an alkyl nitrile. In an unbiased substrate, a methoxy leaving group attached to a stereogenic secondary carbon atom led to the cyclization product wi...

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Bibliografiset tiedot
Päätekijät: La Cruz, Thomas E., Rychnovsky, Scott D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2496923/
https://ncbi.nlm.nih.gov/pubmed/16438522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo052166u
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