An anti-coagulation agent Futhan preferentially targets GABA(A) receptors in lungepithelia: implication in treating asthma

Futhan is a serine protease inhibitor and medicine in the treatment of disseminated intravascular coagulation (DIC) and acute pancreatitis. It is metabolized quickly in vivo. Here we show that Futhan reversibly inhibits NMDA receptors in hippocampal neurons and GABA(A) receptors both in hippocampal...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Xuanmao, Li, Minghua, Xiong, Zhi-Gang, Orser, Beverley A, MacDonald, John F, Lu, Wei-Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2011
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230258/
https://ncbi.nlm.nih.gov/pubmed/22162781
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