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Diarylamidines: High potency inhibitors of acid-sensing ion channels
Acid-sensing ion channels (ASICs) are proton-gated cation channels that are predominantly expressed in the nervous system. ASICs are involved in a number of neurological diseases such as pain, ischemic stroke and multiple sclerosis but limited tools are available to target these channels and provide...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3846926/ https://ncbi.nlm.nih.gov/pubmed/20114056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.01.011 |
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