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An anti-coagulation agent Futhan preferentially targets GABA(A) receptors in lungepithelia: implication in treating asthma

Futhan is a serine protease inhibitor and medicine in the treatment of disseminated intravascular coagulation (DIC) and acute pancreatitis. It is metabolized quickly in vivo. Here we show that Futhan reversibly inhibits NMDA receptors in hippocampal neurons and GABA(A) receptors both in hippocampal...

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Détails bibliographiques
Auteurs principaux: Chen, Xuanmao, Li, Minghua, Xiong, Zhi-Gang, Orser, Beverley A, MacDonald, John F, Lu, Wei-Yang
Format: Artigo
Langue:Inglês
Publié: e-Century Publishing Corporation 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230258/
https://ncbi.nlm.nih.gov/pubmed/22162781
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