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The General Anesthetic Propofol Slows Deactivation and Desensitization of GABA(A) Receptors

Propofol (2,6-di-isopropylphenol) has multiple actions on GABA(A) receptor function that act in concert to potentiate GABA-evoked currents. To understand how propofol influences inhibitory IPSCs, we examined the effects of propofol on responses to brief applications of saturating concentrations of G...

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Pubblicato in:J Neurosci
Autori principali: Bai, Donglin, Pennefather, Peter S., MacDonald, John F., Orser, Beverley A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784967/
https://ncbi.nlm.nih.gov/pubmed/10594047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-24-10635.1999
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