Evolutionary Modeling of Combination Treatment Strategies To Overcome Resistance to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer

[Image: see text] Many initially successful anticancer therapies lose effectiveness over time, and eventually, cancer cells acquire resistance to the therapy. Acquired resistance remains a major obstacle to improving remission rates and achieving prolonged disease-free survival. Consequently, novel...

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Main Authors: Mumenthaler, Shannon M., Foo, Jasmine, Leder, Kevin, Choi, Nathan C., Agus, David B., Pao, William, Mallick, Parag, Michor, Franziska
פורמט: Artigo
שפה:Inglês
יצא לאור: American Chemical Society 2011
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230244/
https://ncbi.nlm.nih.gov/pubmed/21995722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp200270v
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