Human small-cell lung cancers show amplification and expression of the N-myc gene.

We have found that 6 of 31 independently derived human small-cell lung cancer (SCLC) cell lines have 5- to 170-fold amplified N-myc gene sequences. The amplification is seen with probes from two separate exons of N-myc, which are homologous to either the second or the third exon of the c-myc gene. A...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Nau, M M, Brooks, B J, Carney, D N, Gazdar, A F, Battey, J F, Sausville, E A, Minna, J D
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1986
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323017/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2869482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.4.1092
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