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Human small-cell lung cancers show amplification and expression of the N-myc gene.
We have found that 6 of 31 independently derived human small-cell lung cancer (SCLC) cell lines have 5- to 170-fold amplified N-myc gene sequences. The amplification is seen with probes from two separate exons of N-myc, which are homologous to either the second or the third exon of the c-myc gene. A...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1986
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323017/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2869482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.4.1092 |
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