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Transcriptional activation and DNase I hypersensitive sites are associated with selective expression of the gastrin-releasing peptide gene.

The gastrin-releasing peptide (GRP) is a neuropeptide hormone and growth factor produced normally by neural and neuroendocrine cells, as well as by human small-cell lung cancer (SCLC) tumors and derived cell lines. This study compares the structure of the human prepro-GRP gene in four SCLC cell line...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Markowitz, S, Krystal, G, Lebacq-Verheyden, A M, Way, J, Sausville, E A, Battey, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1988
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303587/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2843572/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113683
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