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miRNA Expression Profiling of the Murine TH-MYCN Neuroblastoma Model Reveals Similarities with Human Tumors and Identifies Novel Candidate MiRNAs

BACKGROUND: MicroRNAs are small molecules which regulate gene expression post-transcriptionally and aberrant expression of several miRNAs is associated with neuroblastoma, a childhood cancer arising from precursor cells of the sympathetic nervous system. Amplification of the MYCN transcription facto...

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Autors principals: Terrile, Marta, Bryan, Kenneth, Vaughan, Lynsey, Hallsworth, Albert, Webber, Hannah, Chesler, Louis, Stallings, Raymond L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229581/
https://ncbi.nlm.nih.gov/pubmed/22164278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028356
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