Widespread Dysregulation of MiRNAs by MYCN Amplification and Chromosomal Imbalances in Neuroblastoma: Association of miRNA Expression with Survival

MiRNAs regulate gene expression at a post-transcriptional level and their dysregulation can play major roles in the pathogenesis of many different forms of cancer, including neuroblastoma, an often fatal paediatric cancer originating from precursor cells of the sympathetic nervous system. We have an...

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Auteurs principaux: Bray, Isabella, Bryan, Kenneth, Prenter, Suzanne, Buckley, Patrick G., Foley, Niamh H., Murphy, Derek M., Alcock, Leah, Mestdagh, Pieter, Vandesompele, Jo, Speleman, Frank, London, Wendy B., McGrady, Patrick W., Higgins, Desmond G., O'Meara, Anne, O'Sullivan, Maureen, Stallings, Raymond L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773120/
https://ncbi.nlm.nih.gov/pubmed/19924232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007850
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