Recruitment of Oct4 Protein to UV-Damaged Chromatin in Embryonic Stem Cells

BACKGROUND: Oct4 is a specific marker of embryonic stem cell (ESC) pluripotency. However, little is known regarding how Oct4 responds to DNA damage. Here, we investigated whether Oct4 recognizes damaged chromatin in mouse ESCs stably expressing GFP-Oct4. These experiments should contribute to the kn...

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Bibliografiska uppgifter
Huvudupphovsmän: Bártová, Eva, Šustáčková, Gabriela, Stixová, Lenka, Kozubek, Stanislav, Legartová, Soňa, Foltánková, Veronika
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229488/
https://ncbi.nlm.nih.gov/pubmed/22164208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027281
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