Recruitment of Oct4 Protein to UV-Damaged Chromatin in Embryonic Stem Cells

BACKGROUND: Oct4 is a specific marker of embryonic stem cell (ESC) pluripotency. However, little is known regarding how Oct4 responds to DNA damage. Here, we investigated whether Oct4 recognizes damaged chromatin in mouse ESCs stably expressing GFP-Oct4. These experiments should contribute to the kn...

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Main Authors: Bártová, Eva, Šustáčková, Gabriela, Stixová, Lenka, Kozubek, Stanislav, Legartová, Soňa, Foltánková, Veronika
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229488/
https://ncbi.nlm.nih.gov/pubmed/22164208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027281
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