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Differentiation-Independent Fluctuation of Pluripotency-Related Transcription Factors and Other Epigenetic Markers in Embryonic Stem Cell Colonies

Embryonic stem cells (ESCs) maintain their pluripotency through high expression of pluripotency-related genes. Here, we show that differing levels of Oct4, Nanog, and c-myc proteins among the individual cells of mouse ESC (mESC) colonies and fluctuations in these levels do not disturb mESC pluripote...

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Dettagli Bibliografici
Autori principali: Šustáčková, Gabriela, Legartová, Soňa, Kozubek, Stanislav, Stixová, Lenka, Pacherník, Jiří, Bártová, Eva
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295859/
https://ncbi.nlm.nih.gov/pubmed/21609209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2011.0085
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