Recruitment of Oct4 Protein to UV-Damaged Chromatin in Embryonic Stem Cells

BACKGROUND: Oct4 is a specific marker of embryonic stem cell (ESC) pluripotency. However, little is known regarding how Oct4 responds to DNA damage. Here, we investigated whether Oct4 recognizes damaged chromatin in mouse ESCs stably expressing GFP-Oct4. These experiments should contribute to the kn...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bártová, Eva, Šustáčková, Gabriela, Stixová, Lenka, Kozubek, Stanislav, Legartová, Soňa, Foltánková, Veronika
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229488/
https://ncbi.nlm.nih.gov/pubmed/22164208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027281
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