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Recruitment of Oct4 Protein to UV-Damaged Chromatin in Embryonic Stem Cells
BACKGROUND: Oct4 is a specific marker of embryonic stem cell (ESC) pluripotency. However, little is known regarding how Oct4 responds to DNA damage. Here, we investigated whether Oct4 recognizes damaged chromatin in mouse ESCs stably expressing GFP-Oct4. These experiments should contribute to the kn...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3229488/ https://ncbi.nlm.nih.gov/pubmed/22164208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027281 |
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