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Targeting of eEF1A with Amaryllidaceae isocarbostyrils as a strategy to combat melanomas
Melanomas display poor response rates to adjuvant therapies because of their intrinsic resistance to proapoptotic stimuli. This study indicates that such resistance can be overcome, at least partly, through the targeting of eEF1A elongation factor with narciclasine, an Amaryllidaceae isocarbostyril...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Federation of American Societies for Experimental Biology
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3229423/ https://ncbi.nlm.nih.gov/pubmed/20643906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-162263 |
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