The Amaryllidaceae Isocarbostyril Narciclasine Induces Apoptosis By Activation of the Death Receptor and/or Mitochondrial Pathways in Cancer Cells But Not in Normal Fibroblasts

Our study has shown that the Amaryllidaceae isocarbostyril narciclasine induces marked apoptosis-mediated cytotoxic effects in human cancer cells but not in normal fibroblasts by triggering the activation of the initiator caspases of the death receptor pathway (caspase-8 and caspase-10) at least in...

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Detalhes bibliográficos
Main Authors: Dumont, Patrick, Ingrassia, Laurent, Rouzeau, Sébastien, Ribaucour, Fabrice, Thomas, Stéphanie, Roland, Isabelle, Darro, Francis, Lefranc, Florence, Kiss, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1993861/
https://ncbi.nlm.nih.gov/pubmed/17898872
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