BIM expression in treatment naïve cancers predicts responsiveness to kinase inhibitors

Cancers with specific genetic mutations are susceptible to selective kinase inhibitors. However, there is wide spectrum of benefit among cancers harboring the same sensitizing genetic mutations. Herein, we measured apoptotic rates among cell lines sharing the same driver oncogene following treatment...

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Main Authors: Faber, Anthony, Corcoran, Ryan B., Ebi, Hiromichi, Sequist, Lecia V., Waltman, Belinda A., Chung, Euiheon, Incio, Joao, Digumarthy, Subba R., Pollack, Sarah F., Song, Youngchul, Muzikansky, Alona, Lifshits, Eugene, Roberge, Sylvie, Coffman, Erik J., Benes, Cyril, Gómez, Henry, Baselga, Jose, Arteaga, Carlos L., Rivera, Miguel N., Dias-Santagata, Dora, Jain, Rakesh K., Engelman, Jeffrey A.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229203/
https://ncbi.nlm.nih.gov/pubmed/22145099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-11-0106
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