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BIM expression in treatment naïve cancers predicts responsiveness to kinase inhibitors

Cancers with specific genetic mutations are susceptible to selective kinase inhibitors. However, there is wide spectrum of benefit among cancers harboring the same sensitizing genetic mutations. Herein, we measured apoptotic rates among cell lines sharing the same driver oncogene following treatment...

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Detalhes bibliográficos
Main Authors: Faber, Anthony, Corcoran, Ryan B., Ebi, Hiromichi, Sequist, Lecia V., Waltman, Belinda A., Chung, Euiheon, Incio, Joao, Digumarthy, Subba R., Pollack, Sarah F., Song, Youngchul, Muzikansky, Alona, Lifshits, Eugene, Roberge, Sylvie, Coffman, Erik J., Benes, Cyril, Gómez, Henry, Baselga, Jose, Arteaga, Carlos L., Rivera, Miguel N., Dias-Santagata, Dora, Jain, Rakesh K., Engelman, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229203/
https://ncbi.nlm.nih.gov/pubmed/22145099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-11-0106
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